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Grazia Cottone

Associate Professor

Former affiliation
  • 843 Citations
  • 15 h-Index
20042020

Research output per year

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Research Output

2020

Hepatitis B protein HBx binds the DLEU2 lncRNA to sustain cccDNA and host cancer-related gene transcription

Cottone, G., Levrero, M., Guerrieri, F., Pallocca, M., Floriot, O., Salerno, D., Plissonnier, M-L., Paturel, A., Alfano, V., Jeddari, S., Zeisel, M., Chiodo, L. & Belloni, L., 2020, In : Gut. p. 1-9 9 p.

Research output: Contribution to journalArticle

Understanding and Controlling Food Protein Structure and Function in Foods: Perspectives from Experiments and Computer Simulations

Cottone, G., Carloni, P., Mohammad Hosseini Naveh, Z., Gulzar, M., Barroso Da Silva, F. L., Mackernan, D., Jacquier, J. C., Lobaskin, V., Foegeding, E. A., Cheung, D., Radhakrishnan, R., Donnini, S. & Santiso, E. E., 2020, In : Annual review of food science and technology. 11, p. 365-387 22 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019

More than a Confinement: “Soft” and “Hard” Enzyme Entrapment Modulates Biological Catalyst Function

Cottone, G., Cupane, A., Marchetti, M., Abbruzzetti, S., Ronda, L., Campanini, B., Bettati, S., Viappiani, C., Mozzarelli, A., Giuffrida, S., Bruno, S. & Giuffrida, S., 2019, In : Catalysts. 9, p. 1-29 29 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018
2 Citations (Scopus)

Closed-Locked and Apo-Resting State Structures of the Human α7 Nicotinic Receptor: A Computational Study

Cottone, G., Maragliano, L., Malliavin, T. E., Chiodo, L., Giuffrida, S. & Giuffrida, S., 2018, In : Journal of Chemical Information and Modeling. 58, p. 2278-2293 16 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2017

A possible desensitized state conformation of the human α7 nicotinic receptor: A molecular dynamics study

Cottone, G., Maragliano, L., Cottone, G., Malliavin, T. E. & Chiodo, L., 2017, In : Biophysical Chemistry. 229, p. 99-109 11 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
5 Citations (Scopus)

The water association band as a marker of hydrogen bonds in trehalose amorphous matrices

Cordone, L., Cottone, G., Cottone, G. & Giuffrida, S., 2017, In : Physical Chemistry Chemical Physics. 19, p. 4251-4265 15 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2015

A Structural Model of the Human α7 Nicotinic Receptor in an Open Conformation

Cottone, G., Maragliano, L., Cottone, G., Ciccotti, G., Malliavin, T. E. & Chiodo, L., 2015, In : PLoS One.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Observing myoglobin proteinquake with an X-ray free-electron laser

Cupane, A., Levantino, M. & Cottone, G., 2015. 1 p.

Research output: Contribution to conferenceOther

Proteins in saccharides matrices and the trehalose peculiarity: Biochemical and biophysical properties

Cupane, A., Emanuele, A., Cordone, L., Cottone, G., Levantino, M., Cottone, G. & Giuffrida, S., 2015, In : Current Organic Chemistry. 19, p. 1684-1706 23 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Ultrafast myoglobin structural dynamics observed with an X-ray free-electron laser

Cottone, G., Levantino, M., Cupane, A., Schirò, G., Lemke, H. T., Zhu, D., Glownia, J. M., Ihee, H., Chollet, M. & Cammarata, M., 2015, In : Nature Communications. 6, 6 p.

Research output: Contribution to journalArticle

94 Citations (Scopus)
2014

Conformational changes in acetylcholine binding protein investigated by Temperature Accelerated Molecular Dynamics

Cottone, G., Maragliano, L., Naveh, Z. M. H., Cottone, G., Ciccotti, G. & Malliavin, T. E., 2014, In : PLoS One. 9, 16 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Large scale motions in models of human nicotinic receptors

Cottone, G., 2014, CINECA HPC REPORT 2014. 1 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Molecular dynamics simulations of a new model of human a7 nicotinic receptor

Cottone, G., 2014. 1 p.

Research output: Contribution to conferenceOther

Protein Bioprotection in disaccharides: a multiscale approach

Cottone, G., 2013. 1 p.

Research output: Contribution to conferenceOther

Water effects on saccharide matrices studied with molecular dynamics

Cottone, G., 2013. 1 p.

Research output: Contribution to conferenceOther

2012

Exploring the dynamics of AChBP unbound and bound to the Lobeline partial agonist

Cottone, G., 2012. 0 p.

Research output: Contribution to conferenceOther

8 Citations (Scopus)

Water effects on trehalose matrices studied through Molecular Dynamics

Cottone, G., Cordone, L. & Giuffrida, S., 2012. 1 p.

Research output: Contribution to conferenceOther

2011
9 Citations (Scopus)

MbCo in Saccharide Solid Amorphous Systems: A Combined FTIR and SAXS Study

Cottone, G., Cordone, L. & Giuffrida, S., 2011. 1 p.

Research output: Contribution to conferenceOther

Proteins in Amorphous Saccharides: Structural and Dynamical Insights on Bioprotection

Cordone, L., Cottone, G., Cottone, G., Longo, A. & Giuffrida, S., 2011, Dynamics of Biological Macromolecules by Neutron Scattering. p. 66-78 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

42 Citations (Scopus)

The electric properties of ionic solutions: a molecular dynamics (preliminary) study

Cottone, G., 2011. 1 p.

Research output: Contribution to conferenceOther

The electric properties of ionic solutions: a molecular dynamics (preliminary) study

Cottone, G., 2011. 1 p.

Research output: Contribution to conferenceOther

2010

A calorimetric study of ternary protein-trehalose-water systems: matrix glass transition and protein thermal denaturation

Cupane, A., Cordone, L., Cottone, G., Bellavia, G. & Giuffrida, S., 2010, p. 17-17. 1 p.

Research output: Contribution to conferenceOther

FTIR and SAXS study on MBCO-saccharide amorphous systems: protein-matrix reciprocal effects

Cottone, G., Cordone, L. & Giuffrida, S., 2010. 1 p.

Research output: Contribution to conferenceOther

Mapping CO diffusion paths in Myoglobin with the Single Sweep Method

Cottone, G., 2010. 1 p.

Research output: Contribution to conferenceOther

Mapping the network of pathways of Co diffusion in myoglobin

Cottone, G., Maragliano, L., Vanden-Eijnden, E. & Ciccotti, G., 2010, In : Journal of the American Chemical Society. 2010-01, p. 1010-1017 7 p.

Research output: Contribution to journalArticle

92 Citations (Scopus)

Matrix glass transition and embedded protein denaturation: effect of trehalose on different proteins

Cordone, L., Cupane, A., Cottone, G., Bellavia, G. & Giuffrida, S., 2010. 1 p.

Research output: Contribution to conferenceOther

17 Citations (Scopus)
2009

Atomistic MD simulation of proteins in complex solvents

Cottone, G., 2009. 1 p.

Research output: Contribution to conferenceOther

FTIR Study on Reciprocal Protein↔Matrix effects in dry amorphous saccharide systems

Cottone, G., Cordone, L. & Giuffrida, S., 2009. 1 p.

Research output: Contribution to conferenceOther

MbCO↔matrix reciprocal effects in low hydration amorphous saccharide systems: a FTIR study

Cordone, L., Cottone, G. & Giuffrida, S., 2009. 1 p.

Research output: Contribution to conferenceOther

Relationship between the Glass Transition of Myoglobin-Water-Disaccharide systems and Protein Thermal Denaturation

Cottone, G., Cupane, A., Cordone, L., Bellavia, G. & Giuffrida, S., 2009. 1 p.

Research output: Contribution to conferenceOther

SAXS and FTIR study on MbCO-Saccharide amorphous systems

Cordone, L., Cottone, G., Panzica, M. & Giuffrida, S., 2009. 1 p.

Research output: Contribution to conferenceOther

Thermal Behavior of dry and hydrated MbCO crowded systems

Cottone, G., Cordone, L. & Giuffrida, S., 2009. 1 p.

Research output: Contribution to conferenceOther

34 Citations (Scopus)

Thermal Denaturation of Myoglobin in Water–Sugar Matrices and Relationship with the Glass Transition of the System

Cordone, L., Cupane, A., Cottone, G., Bellavia, G. & Giuffrida, S., 2009. 1 p.

Research output: Contribution to conferenceOther